Side Effect Management

Managing vomiting and nausea

The most common and most serious side effects of LUTATHERA include: vomiting, nausea, decreased blood cell counts, increased liver enzymes, decreased blood potassium levels, and increased glucose in the bloodstream.

If you have a side effect that bothers you or doesn’t go away, tell your healthcare team.

If you experience vomiting after receiving LUTATHERA:

  • Get liquids in the form of ice chips or frozen juice chips because these can be taken slowly
  • Ask your care team if anti-vomiting medicines in the form of dissolving tablets or suppositories would help you
  • If you do vomit, start taking in 1 teaspoon of cool liquid every 10 minutes after it stops. Slowly increase the amount to 1 tablespoon. If you are able to keep the liquid down after an hour or so, try larger amounts

If you experience nausea after receiving LUTATHERA:

  • Eat smaller, more frequent meals that are easy to eat and high in calories (use butter, oils, syrups, sauces, and milk in foods to raise calories)
  • Eat food cold or at room temperature to decrease its smell and taste
  • Drink clear liquids served cold and sipped slowly
  • Suck on hard candy with pleasant smells, such as lemon drops or mints, to get rid of bad tastes
  • Eat bland foods, such as dry toast and crackers


LUTATHERA® (lutetium Lu 177 dotatate) is a prescription medicine used to treat adults with a type of cancer known as gastroenteropancreatic neuroendocrine tumors (GEP-NETs) that are positive for the hormone receptor somatostatin, including GEP-NETs in the foregut, midgut, and hindgut.

Patient Discussion Guide
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