Understanding GEP-NETs

What are gastroenteropancreatic neuroendocrine tumors (GEP-NETs)?

In order to understand GEP-NETs, it’s important to first understand neuroendocrine tumors (NETs).

NETs are tumors that can occur anywhere in the body, most often in the small intestine, pancreas, and rectum. NETs typically form in cells that make hormones. Some of these tumors make extra amounts of hormones that may cause symptoms of disease such as flushing and diarrhea.

Not all NETs are the same. They can be different in size, and some types grow faster than others.

GEP-NETs are cancers that form in the pancreas or in other parts of the gastrointestinal tract including the stomach, small intestine, colon, rectum, and appendix.


LUTATHERA® (lutetium Lu 177 dotatate) is a prescription medicine used to treat adults with a type of cancer known as gastroenteropancreatic neuroendocrine tumors (GEP-NETs) that are positive for the hormone receptor somatostatin, including GEP-NETs in the foregut, midgut, and hindgut.

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